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CASE STUDY:
65-Year-Old Male with 6 Weeks of Progressive Dyspnea on Exertion
CLINICAL INFORMATION
HISTORY OF PRESENT ILLNESS
A 65-year-old male without a history of underlying lung disease
presented with progressive dyspnea on exertion over 6 weeks. The
patient was in his normal state of good health and active prior
to the onset of his shortness of breath. He denied the presence
of joint pain, skin lesions, myalgias, or any systemic symptoms
like fever, fatigue, or generalized malaise that would suggest a
connective tissue disease.
PAST MEDICAL HISTORY
The patient's past medical history was unremarkable. He was taking
no medications associated with interstitial lung disease and had
no drug allergies.
SOCIAL HISTORY
The patient was a former smoker, and he denied any occupational exposures or bird exposures.
FAMILY HISTORY
The patient denied the presence of any interstitial lung diseases or connective tissue diseases in his immediate family members.
PHYSICAL EXAMINATION
On examination, the patient was a pleasant male, appearing his
stated age and in no acute distress. His vital signs are listed
below:
| · |
Temperature |
99.0° F |
| · |
Pulse |
95 bpm |
| · |
Blood pressure |
132/70 mm Hg |
| · |
Respirations |
29 bpm |
| · |
SaO2 |
93% RA |
Examination of his head and neck was unremarkable. Auscultation of his chest revealed bibasilar and axillary crackles. His heart had a regular rate and rhythm without murmurs, rubs, or gallops, and his abdomen was benign. He had no cyanosis, clubbing, or edema of the extremities.
LABORATORY AND SEROLOGIC TESTING
| Pulmonary Function Studies |
FVC % Predicted |
DLCO % Predicted |
| 60% |
40% |
| Room Air Arterial Blood Gas Analysis |
| pH |
pCO2 |
pO2 |
HCO3* |
SaO2 |
| 7.46 |
32 mm Hg |
64 mm Hg |
23 mmol/L |
92% |
* Calculated
| · |
WBC |
5.9 x 103 / mm3 |
| · |
Blood Culture |
No growth |
| · |
Sputum cultures |
Normal flora |
HIGH-RESOLUTION COMPUTED TOMOGRAPHY
A high-resolution computed tomography (HRCT)
scan with 2 mm cuts of the lung fields demonstrated peripheral
honeycomb changes and traction bronchiectasis, most prominent in
the lower lung zones.
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