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Carl: An Interactive NSCLC Case

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Momen M. Wahidi, MD, FCCP and W. Dean Wallace, MD

Molecular diagnostics and targeted therapy rely on adequate tissue biopsy. Learn from this case and better meet the needs of your multidisciplinary partners.

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Pete: An Interactive NSCLC Case

cme-ce
Momen M. Wahidi, MD, FCCP and W. Dean Wallace, MD

Glimpse the world of tissue processing and analysis from the pathology perspective.

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2-minute Case Assessment

Lyman is a 75-year-old former smoker, married, retired computer developer with a history of asthma, hypertension and diabetes, and presents with a cough. What's your diagnosis?

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Presented by: Momen M. Wahidi, MD, FCCP and W. Dean Wallace, MD

CHEST NSCLC 2016

Biomarker-driven targeted therapy of patients with NSCLC requires accurate diagnosis and staging. The pulmonary care team must acquire adequate biopsy tissue to enable histology, immunofluorescence and molecular biomarker testing. Presented in Los Angeles, California - October 2016.

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CHEST NSCLC 2016

Overview of staging: http://www.cancer.org/cancer/lungcancer-non-smallcell/detailedguide/non-small-cell-lung-cancer-staging

Overview of diagnosis: http://www.dana-farber.org/Adult-Care/Treatment-and-Support/Non-Small-Cell-Lung-Cancer/How-We-Diagnose-Non-Small-Cell-Lung-Cancer.aspx

NCCN NSCLC Guidelines: http://www.nccn.org/professionals/physician_gls/pdf/nscl.pdf

Detterbeck FC, Mazzone PJ, Naidich DP, Bach PB. Screening for Lung Cancer: Diagnosis and Management of Lung Cancer, 3rd ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. Chest. 2013;143(5 Suppl):e78S-92S. https://www.ncbi.nlm.nih.gov/pubmed/23649455

Leighl NB, Rekhtman N, Biermann WA, et al. Molecular Testing for Selection of Patients with Lung Cancer for Epidermal Growth Factor Receptor and Anaplastic Lymphoma Kinase Tyrosine Kinase Inhibitors: American Society of Clinical Oncology endorsement of the College of American Pathologists/International Association for the Study of Lung Cancer/Association for Molecular Pathology Guideline. J Clin Oncol. 2014;32(32):3673-3679. https://www.ncbi.nlm.nih.gov/pubmed/25311215

Schneider F, Smith MA, Lane MC, Pantanowitz L, Dacic S, Ohori NP. Adequacy of Core Needle Biopsy Specimens and Fine-Needle Aspirates for Molecular Testing of Lung Adenocarcinomas. Am J Clin Pathol. 2015;143(2):193-200. https://www.ncbi.nlm.nih.gov/pubmed/25596245

Silvestri GA, Gonzalez AV, Jantz MA, et al. Methods for Staging Non-Small Cell Lung Cancer: Diagnosis and Management of Lung Cancer, 3rd ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. Chest. 2013;143(5 Suppl):e211S-250S. https://www.ncbi.nlm.nih.gov/pubmed/23649440

Wahidi MM, Herth F, Yasufuku K, et al. Technical Aspects of Endobronchial Ultrasound Guided Transbronchial Needle Aspiration: CHEST Guideline and Expert Panel Report. Chest. 2016;149(3):816-835. https://www.ncbi.nlm.nih.gov/pubmed/26402427

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