Image Library

Image 22
UIP in Rheumatoid Lung

This low-magnification view of the lung biopsy shows significant structural remodeling with confluent areas of fibrosis (F). Microscopic honeycombing (MHC) is the hallmark of permanent structural remodeling. Note the lobules that are relatively spared, producing the so-called "temporal heterogeneity" of the UIP pattern. This UIP pattern differs microscopically from that of IPF, based on the infrequent occurrence of fibroblastic foci and the abundance of chronic inflammation (CI).

<< back to gallery